Jie Zan Associate Professor

School: School of Biomedicine and Pharmaceutical Science

Supervisor category: Master supervisor

Research direction: tumor immunity, cerebrovascular disease and monoclonal antibody targeted drugs

E-mail:zanj@gdut.edu.cn

Graduate Admission School:School of Biomedicine and Pharmaceutical Science

Personal brief introduction:

Jie Zan, PhD, Associate Professor, Excellent Young Teacher Recruiting Plan A of Guangdong University of Technology, Visiting scholar of University of British Columbia, graduated from Zhejiang University, He primarily focuses on the research of the immunological pathogenesis of tumors, cerebrovascular diseases and other major diseases, as well as the research and development of molecular targeted drugs and in vitro accompaniment diagnostic kits. At present, he has published about twenty SCI articals and his research works have been supported by National Natural Science Foundation of China, Guangdong Natural Science Foundation of China, China Postdoctoral Science Foundation, Guangzhou Basic and Applied Basic Research Project, and so on.

Subject areas

Science degree: Pharmaceutical Engineering

Major Degree: Materials and Chemical Engineering (Biomedicine)

Education background

2005.9-2010.6 School of Veterinary Medicine, Huazhong Agricultural University, Animal Medicine (Bachelor degree)  

2010.9-2016.10 College of Animal Science, Zhejiang University, Preventive Veterinary (Master and Doctor degree)

2016.11-2018.10 School of Biomedicine, Guangdong University of Technology, Biomedicine, postdoctor

2018.11-2019.07 University of British Columbia, Biomedicine, Visiting Scholar

Work experience

2019.07-Present Associate professor, School of Biomedicine, Guangdong University of Technology

Main honor

Advanced Scientist of Guangdong University of Technology in 2018

Publications

Min-Yi Lu; Jin-Rong Wu; Rui-Bing Liang; Yu-Peng Wang; You-Cai Zhu; Zi-Ting Ma; Hao Zhang; Jie Zan*, Wen Tan*, Upregulation of miR-219a-5p Decreases Cerebral Ischemia/Reperfusion Injury In Vitro by Targeting Pde4d. Journal of stroke and cerebrovascular diseases, (2020) 104801

Linbo Zheng; Xialin Tang; Minyi Lu; Shuangxi Sun; Shanshan Xie; Jun Cai; Jie Zan*, microRNA-421-3p prevents inflammatory response in cerebral ischemia/reperfusion injury through targeting m6A Reader YTHDF1 to inhibit p65 mRNA translation. International immunopharmacology 88 (2020) 106937.

Jie Zan#; Ruixian Xu#; Xialin Tang; Minyi Lu; Shanshan Xie; Jun Cai; Zhi Huang*; Jinyang Zhang*, RNA helicase DDX5 suppresses IFN-I antiviral innate immune response by interacting with PP2A-Cβ to deactivate IRF3. Experimental cell research 396 (2020) 112332.

Zan,jie#; Zhang, Hao#;Lu Min-Yi; Beng, Hui-Min; Zhon, Kai-Lun; Sun Xiao-Ou;Tan, Wen*,Isosteviol sodium injection improves outcomes by modulating TLRs/NF-κB dependent inflammatory responses following experimental traumatic brain injury in rats.Neuroreport, 2018, 29(10):1.

Zan, Jie#; Zhang, Hao#; Gu, Ai-Ping#; Zhong, Kai-Lun; Lu, Min-Yi; Bai, Xiao-Xin; Zhang, Jin-Yang; Cai, Jun*,Yin Yang 1 Dynamically Regulates Antiviral Innate Immune Responses During Viral Infection, Cellular Physiology and Biochemistry, 2017.11.20, 44(2): 607~617.

Zan, Jie; Liu, Song; Sun, Dong-Nan; Mo, Kai-Kun; Yan, Yan; Liu, Juan; Hu, Bo-Li; Gu, Jin-Yan*; Liao, Min*; Zhou, Ji-Yong, Rabies Virus Infection Induces Microtubule Depolymerization to Facilitate Viral RNA Synthesis by Upregulating HDAC6, Frontiers in Cellular and Infection Microbiology, 2017.4.26, 7.

Zan, Jie; An, Shu-Ting; Mo, Kai-Kun; Zhou, Jian-Wei; Liu, Juan; Wang, Hai-Long; Yan, Yan; Liao, Min*; Zhou, Ji-Yong, Rabies virus inactivates cofilin to facilitate viral budding and release, Biochemical and Biophysical Research Communications, 2016.9.2, 477(4):1045~1050.

Zan, Jie; Liu, Juan; Zhou, Jian-Wei; Wang, Hai-Long; Mo, Kai-Kun; Yan, Yan; Xu, Yun-Bin; Liao, Min; Su, Shuo; Hu, Rong-Liang; Zhou, Ji-Yong, Rabies virus matrix protein induces apoptosis by targeting mitochondria, Experimental Cell Research, 2016.9.10, 347(1):83~94.

Wang, Shuai#; Zan, Jie# (co-first author); Wu, Mingjie; Zhao, Wenting; Li, Zhenwei; Pan, Yanyun; Sun, Zewei; Zhu, Jianhua*, miR-29a promotes scavenger receptor A expression by targeting QKI (quaking) during monocyte-macrophage differentiation, Biochemical and Biophysical Research Communications, 2015.8.14, 464(1):1~6