School of Biomedicine and Pharmaceutical Sciences, Guangdong University of Technology (GDUT), Guangzhou, China.

E-mail:houxd@gdut.edu.cn

Address:Room 205-4, Building of School of Biomedicine and Pharmaceutical Sciences, No. 100, Waihuan Xi Road, Guangzhou Higher Education Mega Center, Panyu District, Guangzhou, P.R China, Post Code: 510006.

Field of Research:

1. Bioresources processing: Acquisition of high value-added products from waste bio-resources (biomass, etc.) based on novel solvents and the related mechanism investigation.

2. Applied biocatalysis and biotransformation: enzymatic synthesis or modification and microbial transformation of natural products (drugs).

Work experiences:

Jan 2019 – Present Associate professor,Biomedicine and Pharmaceutical Sciences, GDUT

Nov 2018- Nov 2019: Visiting researcher, Department of chemical engineering, Imperial College London

Sep 2013 – Dec 2018 Lecturer, School of Chemical Engineering and Light Industry, GDUT

Education Background:

Sep 2009 – Sep 2013 Ph. D. Major in Biochemical Engineering

College of Bioscience and Engineering, South China University of Technology (SCUT)

Sep 2006– Jul 2009B. S. Major in Fermentation Engineering

College of Bioscience and Engineering, SCUT

Selected publications:

1. Kai-Peng Lin, Guo-Jian Feng, Fu-Long Pu,Hou, Xue-Dan*,Shi-Lin Cao, Enhancing the Thermostability of Papain by Immobilizing on Deep Eutectic Solvents-Treated Chitosan With Optimal Microporous Structure and Catalytic Microenvironment. Frontiers in Bioengineering and Biotechnology, 2020, 8.

2. Zi-Jian Huang , Guo-Jian Feng, Kai-Peng Lina , Fu-Long Pu, Yan-Ming Tana , Wei-Chien Tu, Ya-Li Han,Xue-Dan Hou*, Hong-Mei Zhang, Yi Zhang. Significant boost in xylose yield and enhanced economic value with one-pot process using deep eutectic solvent for the pretreatment and saccharification of rice straw. Industrial Crops and Products, 2020, 152:112515.

3.Xue-Dan Hou*, Ao-Lin Li, Kai-PengLin, Yuan-YuanWang, Zhi-YinKuang, Shi-LinCao. Insight into the structure-function relationships of deep eutectic solventsduring rice straw pretreatment. Bioresource Technology, 2018, 249:261-267.

4.Xue-Dan Hou*, Kai-Peng Lin, Ao-Lin Li,Lu-Min Yang, Ming-Hui Fu. Effect of constituents molar ratios of deep eutectic solvents on rice strawfractionation efficiency and the micro-mechanism investigation. Industrial Crops and Products, 2018, 120:322-329.

5. Ao-Lin Li,Xue-Dan Hou*,Kai-Peng Lin, Xuan Zhang, and Ming-Hui Fu.Rice strawpretreatment using deep eutectic solvents with different constituents molar ratios: Biomass fractionation, polysaccharides enzymatic digestion and solvent reuse. Journal of Bioscience and Bioengineering, 2018, 126(3): 346-354.

6.Xue-DanHou*, Guo-Jian Feng, Mei Ye, Chao-Mei Huang, Yi Zhang*. Significantly enhanced enzymatic hydrolysis of rice straw via a highperformancetwo-stage deep eutectic solvents synergistic pretreatment. Bioresource Technology, 2017, 238: 139-146.

7.Xuedan Hou, Jie Xu, Ning Li *, Minhua Zong *. Effect of anion structures on cholinium ionic liquids pretreatment of rice straw and the subsequent enzymatic hydrolysis, Biotechnology and Bioengineering, 2015, 112(1): 65-73.

8.Xuedan Hou, Ning Li*, Minhua Zong*. Renewable bio ionic liquids-water mixtures-mediated selective removal of lignin from rice straw: visualization of changes in composition and cell wall structure; Biotechnology and Bioengineering, 2013, 110 (7), 1895-1902.

9.Xuedan Hou, Ning Li*, Minhua Zong*. Significantly enhancing enzymatic saccharification of rice straw after pretreatment using renewable ionic liquid-water mixtures; Bioresource Technology, 2013, 136: 469-474.

10.Xuedan Hou, Ning Li*, Minhua Zong*. Facile and simple pretreatment of sugarcane bagasse without size reduction using renewable ionic liquids-water mixtures，ACS Sustainable Chemistry and Engineering, 2013, 1(5): 519- 526.

11.Xuedan Hou, Thomas J. Smith, Ning Li*, Minhua Zong*. Novel Renewable Ionic Liquids as Highly Effective Solvents for Pretreatment of Rice Straw Biomass by Selective Removal of Lignin, Biotechnology and Bioengineering, 2012, 109(10):2484-2493.

12.Qiuping Liu,Xuedan Hou(co- first author), Ning Li, Minhua Zong*, Ionic liquids from renewable biomaterials: synthesis, characterization and application in the pretreatment of biomass, Green Chemistry, 2012, 14 (2),304-307.

13.Xuedan Hou, QiuPing Liu, Thomas J. Smith, NingLi, Minhua Zong*. Evaluation of toxicity and biodegradability of cholinium amino acids ionic liquids, PLoS ONE , 2013, 8(3), e59145.

14.WLi;HWu;BGLiu;Xue-DanHou;DJWan;WYLou ;JZhao. Highly efficient and regioselective synthesis of dihydromyricetinesters by immobilized lipase, Journal of Biotechnology, 2015, 199: 31-37.

15.Xue-DanHou,Wen-YongLou*,Li-QiangYan, Min-HuaZong*.Influences of ionic liquids on catalytic performances of papain.Chemical Journal of Chinese Universities,2012, 33: 1245-1251.

16.Xue-DanHou, YiZhang, HuanLiu,NingLi, Min-HuaZong. Enzymatic Synthesis of 5'-Palmitate of 5-Fluorouridine.Chinese Journal of Catalysis, 2011, 32: 1733-1738.

17.Shi-Lin. Cao, W. M. Gu, W. D. Ou-Yang, D. C. Chen, B. Y. Yang, L. H. Lai, Y. J. Liu, J. Zhu, W. J. Chen, Z. Q. Gai,Xue-DanHou, Y. Z. Ma, and Y. X. An, Preparation, Characterization and Application of Rod-Like Chitin Nanocrystal by Usingp-Toluenesulfonic Acid/Choline Chloride Deep Eutectic Solvent as a Hydrolytic Media,Carbohydrate Polymers,2019, 213: 304-310.

Current Research Projects：

1.Deep eutectic solvents mediated lignocellulosic biomass pretreatment based on hemicellulose selectively removal;National Natural Science Foundation of China [grant numbers 21406038].

2. The synergismcorncob componentsdirectional depolymerization andthe products in-suit separation in deep eutectic solvents basedbiphasic system and the mechanism of its enhancement on pretreatment;National Natural Science Foundation of China [grant numbers 22078068].

Awards:

Sep 2012 Excellent Doctor Thesis Innovation Foundation in SCUT

Nov 2012 National Graduate Student Scholarship

Courses Offered:

1."Designof experimentsand data processing" forundergraduate students.

2."Natural product chemistry" forundergraduate students.

3.“Bio-catalysisand Bio-transformation” for graduate student.