Department of Pharmaceutical Engineering,

School of Biomedical and Pharmaceutical Sciences,

Guangdong University of Technology, Guangzhou 510006

E-mail:liuxujie@gdut.edu.cn

Mobile: +86-15001279270

Researchgate:https://www.researchgate.net/profile/Xujie_Liu

Education

Employment

Awards

1.YoungInvestigator Council,Tissue Engineering, 2016(9 out of 450 global applications)

2.ExcellentPostDoctor, Awarded by Graduate School at Shenzhen, Tsinghua University, 2016 (2 out of 25)

3.First Prize of Scholarship,Awarded byTsinghuaUniversity, 2014(Top 10%)

4.First PrizeofExcellentB. S. Dissertation of Hubei Province, 2010 (1 out of 99)

5.Excellent graduate, Awarded by Huazhong University of Science and Technology, 2010

Projects(asPrincipal Investigator)

1.“Nano-biomaterial as drug carrier and drug delivery system” Supported by Guangdong University of Technology, 200,000 Chinese RMB,2020/04-2024/12

2.“Regulation of plasma polymerized surface on osteogenic differentiation of stem cells” Supported by China Postdoctoral Science Foundation (Special Foundation, Grant No.2017T100073), 150,000 Chinese RMB,2017/01-2017/12

3.“Synergistic regulation of surface chemistry and topography gradient by plasma polymerization on cell behavior” Supported by China Postdoctoral Science Foundation (First Class, Grant No.2017M610084), 80,000 Chinese RMB,2017/01-2017/12

4.“Synergistic regulation of surface topography gradient and surface chemistry on cell behavior and the related mechanism”Supported byNational Natural Science Foundation of China (Grant No.31600763), 108,000 Chinese RMB,2017/01-2017/12

5.“A novel dual microsphere based on thiolated chitosan/calcium carbonate for bone tissue engineering” Supported by Project of Basic Research of Shenzhen (Grant No. JCYJ20160531195524566), 300,000 Chinese RMB,2016/08-2018/08

Projects(as participant)

1.“Magnetic cocktail hydrogel for multimodality treatment of triplenegative breast cancer”, Supported byNational Natural Science Foundation of China (Grant No. 81671829),2017/01-2020/12

2.“Guided tissue regeneration of smart hydrogel based on natural ECM and the related mechanism” Supported by the National Key Research and Development Program of China (Grant No. 2016YFC1100100), 2016/07-2020/12

3.“The effects of several inorganic nanoparticles on stem cell differentiation and the related mechanism” Supported byNational Natural Science Foundation of China(Grant No. 51472139),2015/01-2018/12

4.“Natural inorganic polymers and smart functionalized micro-units applied in customized rapid prototyping of bioactive scaffolds” Supported byNational Natural Science Foundation of China and European Community (FP7-NMP-2013-EU-China) Grant (Grant No.51361130032),2013/02-2016/01

Publications (as first author & corresponding author)

1.Xujie Liu, Amita M. Vaidya, Da Sun, Yan Zhang, Nadia Ayat, Andrew Schilb and Zheng Rong Lu, Role of eIF4E on epithelial-mesenchymal transition, invasion, and chemoresistance of prostate cancer cells.Cancer Communications, 2020, 40(2-3):126-131.

2.Xujie Liu, Yong Xie, Shengjun Shi, Qingling Feng, Akash Bachhuka, Xiaodong Guo, Zhending She, Rongwei Tan, Qiang Cai, and Krasimir Vasilev, The co-effect of surface topography gradient fabricated via immobilization of gold nanoparticles and surface chemistry via deposition of plasma polymerized film of allylamine/acrylic acid on osteoblast-like cell behavior.Applied Surface Science, 2019, 473: 838-847.

3.Xujie Liu, Yong Xie, Rui Liu, Ranran Zhang, Hao Yan, Xing Yang, Qianli Huang, Wei He, Bo Yu, Qingling Feng, Shengli Mi, Qiang Cai, A Cyclo-trimer of Acetonitrile Combining Fluorescent Property with Ability to Induce Osteogenesis and Its Potential as Multifunctional Biomaterial.Acta Biomaterialia,2018, 65: 163-173.

4.Xujie Liu, Shengjun Shi, Qingling Feng, Akash Bachhuka, Wei He, Qianli Huang, Ranran Zhang, Xing Yang, Krasimir Vasilev, Surface Chemical Gradient Affects the Differentiation of Human Adipose-Derived Stem Cells via ERK1/2 Signaling Pathway.ACS Applied Materials & Interfaces,2015,7(33): 18473-18482.

5.Xujie Liu, Qingling Feng, Akash Bachhuka, Krasimir Vasilev, Surface Modification by Allylamine Plasma Polymerization Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells.ACS Applied Materials & Interfaces,2014, 6 (12):9733-9741.

6.Yan Chen#,Xujie Liu#, Rui Liu#, Yong Gong, Mingbo Wang, Qianli Huang, Bo Yu, Qingling Feng, Zero-order Controlled Release of BMP2-Derived Peptide P24 from the Chitosan Scaffold by Chemical Grafting Modification Technique for Promotion of Osteogenesis in Vitro and Enhancement of Bone Repair in Vivo,Theranostics, 2017, 7(5): 1072. (#equal contribution authors)

7.Xujie Liu, Wei He, Zhou Fang, Arne Kienzle, Qingling Feng, Influence of Silver Nanoparticles on Osteogenic Differentiation of Human Mesenchymal Stem Cells.Journal of Biomedical Nanotechnology,2014, 10 (7):1277-1285.

8.Xujie Liu, Yan Chen, Qianli Huang, Wei He, Qingling Feng, Bo Yu, A Novel Thermo-Sensitive Hydrogel Based on Thiolated Chitosan/Hydroxyapatite/Beta-Glycerophosphate.Carbohydrate Polymers,2014, 110:62-69.

9.Xujie Liu, Tarek Elkhooly,RanranZhang, Qingling Feng, Akash Bachhuka, Krasimir Vasilev,QiangCai, Shengli Mi, Selective Deposition of CaCO3 on Chemical Gradient Surface Generated by Plasma Polymerization and Its Effect on Cell Adhesion.Materials Letters,2017, 186: 90-93.

10.Xujie Liu, Tarek Elkhooly,Qianli Huang, Wei He,QiangCai, Qingling Feng, Shengli Mi, A facile way to prepare mesoporous spherical calcites controlled by chondroitin sulfate for shape and carboxymethyl chitosan for size.CrystEngComm, 2016, 18 (44): 8582-8586.

11.Xujie Liu, Bo Yu, Qianli Huang, Rui Liu, Qingling Feng,QiangCai, Shengli Mi, In vitro BMP-2 Peptide Release from Thiolated Chitosan Based Hydrogel.International Journal of Biological Macromolecules, 2016, 93: 314-321.

12.Xujie Liu, Qingling Feng, Akash Bachhuka, Krasimir Vasilev, Surface Chemical Functionalities Affect the Behavior of Human Adipose-Derived Stem Cells in Vitro.Applied Surface Science,2013, 270, 473-479.

13.Xujie Liu, Yonghua Gao, Qingling Feng, Regulation of Different Functional Groups on Inorganic Phase of Calcium Carbonate Crystal.Acta Materiae Compositae Sinica, 2012, 1: 003. (in Chinese)

14.Xie, Yong,Xujie Liu*, Xinxin Ma, Yuefeng Duan, Youwei Yao, and Qiang Cai*, Small Titanium-Based MOFs Prepared with the Introduction of Tetraethyl Orthosilicate and Their Potential for Use in Drug Delivery.ACS Applied Materials & Interfaces, 2018, 10 (16): 13325-13332. (* Corresponding author)

15.Xie, Yong, Xinxin Ma, Xujie Liu*, Qingming Long, Yu Wang, Youwei Yao, and Qiang Cai*, Carrier-free microspheres of an anti-cancer drug synthesized via a sodium catalyst for controlled-release drug delivery.Materials, 2018, 11 (2): 281. (* Corresponding author)

16.Fanlu Zhuo,Xujie Liu*, Qin Gao, Ying Wang, Kun Hu, Qiang Cai*, Injectable Hyaluronan-Methylcellulose Composite Hydrogel Crosslinked by Polyethylene Glycol for Central Nervous System Tissue Engineering.Materials Science and Engineering: C, 2017, 81(1):1-7. (* Corresponding author)

17.Feng Zeng, Qiang Cai*,Xujie Liu*, Youwei Yao*, Fanlu Zhuo, Qin Gao, Yong Xie, Yu Wang, Fabrication and mechanical properties of mesoporous silica nanoparticles reinforced magnesium matrix composite.Journal of Alloys and Compounds, 2017, 728:413-423. (* Corresponding author)

Talks

1.“Thiolatedchitosan/BMP-2peptide scaffolds for bone repair” Given at 2015 Chinese Biomaterials Congress, Haikou, 2015

2.“Surface modification by plasma polymerization affects differentiation of human adipose-derived stem cells”Given at International Conference on Regenerative Biomedical Materials (ICRBM 2015), Wuhan, 2015

3.“Thiolated chitosan based composite for bone tissue engineering”, Given at 5^thNational Congress on Biomedical Composite Materials, Nanjing, 2014

4.“A novel thermo-sensitive hydrogel based on thiolated chitosan/hydroxyapatite/ beta-glycerophosphate” Given at 5^thInternational Congress on Ceramics (ICC5), Beijing, 2014

5.“Effects of different functional groups on calcium carbonate mineralization” Given at 7th Student Workshop in Materials Science and Engineering between Tsinghua University-Seoul National University-University of Tokyo, Tokyo, 2011